AFM-T
Generic: Fluorometholone + Tetrahydrozoline
Dose Regimen:
Course Duration:
Alternatives (3)Cheaper & Alternative Brands (0.1%+0.025%)
Same active generic (Fluorometholone + Tetrahydrozoline), same form (Ophthalmic Solution), exact same strength (0.1%+0.025%)
Clinical Prescribing Information
Medical monograph and safety information for healthcare professionals & patients.Indications & Clinical Uses
AFM-T eye drop is indicated in-
Acute and chronic allergic non-infectious conjunctivitis and keratitis with severe swelling and intravascular injection
Non-infectious inflammation of the anterior segment of the eye (including anterior uveitis, episcleritis and scleritis)
Post-operative irritative conditions after strabismus; cataract & glaucoma surgery with supplementary antimicrobial therapy.
Dosage & Administration
Use in adult
: Instill 1 drop into the conjunctival sac 2-3 times daily. The dose may be increased for severe and adult patient to 1 drop hourly for first one to two days.
Use in children
: Safety & effectiveness in children below 2 years of age have not been established.
Contraindications
It is contraindicated in infectious conjunctivitis or keratitis, injuries or ulcerous processes of the cornea, glaucoma, diseases associated with stromal damage of the cornea or sclera & dry eyes.
Side Effects & Adverse Reactions
Mild burning sensation, reversible increase in intraocular pressure, reactive hyperemia, cataract & corneal defects, glaucoma, systemic effects (chronic use).
Warnings & Precautions
Avoid prolonged use. AFM-T should be used after a careful risk benefit evaluation in case of patients with severe blood circulation diseases, metabolic disturbances, under treatment with MAOIs & other potentially hypertensive drugs, history of cataract, herpes simplex infection, rhinitis sicca.
Pharmacology & Mechanism of Action
Fluorometholone is thought to act by the induction of phospholipase A2 inhibitory proteins which control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor arachidonic acid. On the other hand, Tetrahydrozoline is an alpha agonist which constricts the conjunctival blood vessels and thereby relieves the redness of the eye.