Tenafin
Generic: Butenafine Hydrochloride
Application:
Course Duration:
Alternatives (1)Cheaper & Alternative Brands (1%)
Same active generic (Butenafine Hydrochloride), same form (Cream), exact same strength (1%)
Clinical Prescribing Information
Medical monograph and safety information for healthcare professionals & patients.Indications & Clinical Uses
Fintop cream is indicated for the topical treatment of the following superficial dermatophytosis: Interdigital tinea pedis (athlete's foot); Tinea corporis (ringworm); Tinea cruris (jock itch) due to E. floccosum, T. mentagrophytes, T. rubrum, and T. tonsurans.
Dosage & Administration
In the treatment of interdigital tinea pedis, Butenafine should be applied twice daily for 7 days or once daily for 4 weeks. Patients with tinea corporis or tinea cruris should apply Butenafine once daily for two weeks. Sufficient Butenafine cream should be applied to cover affected areas and immediately surrounding skin of patients with interdigital tinea pedis, tinea corporis and tinea cruris.
Contraindications
Butenafine Hydrochloride is contraindicated in individuals who have known or suspected sensitivity to this cream or any of its components.
Side Effects & Adverse Reactions
Rarely local mild burning or irritation may be experienced. Hypersensitivity reactions may occur.
Warnings & Precautions
Fintop cream is not for ophthalmic, oral, or intravaginal use. This is for external use only. If irritation or sensitivity develops with the use of Fintop cream, treatment should be discontinued and appropriate therapy instituted.
Pharmacology & Mechanism of Action
Butenafine is a synthetic antifungal agent that is structurally and pharmacologically related to allylamine antifungals. The exact mechanism of action has not been established, but it is suggested that butenafine's antifungal activity is exerted through the alteration of cellular membranes, which results in increased membrane permeability, and growth inhibition.
Butenafine is mainly active against dermatophytes and has superior fungicidal activity against this group of fungi when compared to that of terbinafine, naftifine, tolnaftate, clotrimazole, and bifonazole. It is also active against Candida albicans and this activity is superior to that of terbinafine and naftifine. Butenafine also generates low MICs for Cryptococcus neoformans and Aspergillus spp. as well.