Purisal
Generic: Levosalbutamol
Treatment Duration:
Cheaper & Alternative Brands (0.63 mg/3 ml)
Same active generic (Levosalbutamol), same form (Nebuliser Solution), exact same strength (0.63 mg/3 ml)No other brands are currently registered in Bangladesh for the 0.63 mg/3 ml presentation. Below are available brands for Levosalbutamol in other strengths:
Clinical Prescribing Information
Medical monograph and safety information for healthcare professionals & patients.Indications & Clinical Uses
Actisal is indicated for the treatment or prevention of bronchospasm in adults, adolescents and children 6 years of age and older with reversible obstructive airway disease.
Dosage & Administration
Tablet-
Adults and adolescents above 12 years: 1-2 mg three times daily.
Children (6 -11 years): 1 mg three times daily.
Syrup-
Adults : 5-10 ml three times daily.
Childrn (6-11 years): 5 ml three times daily.
Contraindications
Levosalbutamol is contraindicated in patients with a history of hypersensitivity to levosalbutamol or any of its components.
Side Effects & Adverse Reactions
Hypocalcaemia, palpitation, fine tremors of the skeletal muscle and muscle cramps may occur. The other likely side effects are nausea, vomiting, burning substernal or epigastric pain and diarrhoea.
Warnings & Precautions
Particular caution is advised in acute severe asthma as this effect may be potentiated by hypoxia and by concomitant treatment with xanthine derivatives, steroids and diuretics. Serum potassium levels should be monitored in such situations.
Pharmacology & Mechanism of Action
Levosalbutamol is a single isomer beta 2-agonist that differs from racemic salbutamol by elimination of (S)-salbutamol. Levosalbutamol is an effective bronchodilator whose primary mechanism of action is unimpeded by (S)-salbutamol. Thus, when compared with racemic salbutamol, clinically comparable bronchodilation can be achieved with doses that substantially lessen beta-mediated side effects.