Picosul
Generic: Sodium Picosulfate
Daily Dose:
Course Duration:
Alternatives (24)Cheaper & Alternative Brands (5 mg/5 ml)
Same active generic (Sodium Picosulfate), same form (Oral Solution), exact same strength (5 mg/5 ml)
Clinical Prescribing Information
Medical monograph and safety information for healthcare professionals & patients.Indications & Clinical Uses
Abdolax is indicated in the following conditions-
Constipation of any etiology
Relief from prolonged & recurrent constipation
Bowel clearance before surgery, childbirth or radiological investigations.
Dosage & Administration
For oral administration. The following dosages are recommended to be taken at night to produce evacuation the following morning. It is recommended to start with the lowest dose. The dose may be adjusted up to the maximum recommended dose to produce regular stools. The maximum recommended daily dose should not be exceeded:
10 mg tablet dose
:
Adults and children over 10 years of age: 5-10 mg per day.
Children aged 4-10 years: 2.5-5 mg per day.
Oral Solution (5 mg/5 ml) dose
:
Adults and children over 10 years of age: 5-10 ml or one to two teaspoonful per day.
Children aged 4-10 years: 2.5-5 ml or half to one teaspoonful per day.
Children from One month to 4 years of age: 0.25 ml/kg body weight per day.
Concentrated Oral Solution (7.5 mg/ml) dose
:
Adults and children over 10 years of age: 0.67-1.33 ml per day.
Children aged 4-10 years: 0.33-0.67 ml per day.
Contraindications
Ileus or intestinal obstruction, severe painful and/or feverish acute abdominal conditions (e.g. appendicitis) potentially associated with nausea and vomiting, acute inflammatory bowel diseases, severe dehydration, known hypersensitivity to Sodium Picosulfate or any other component of the product.
Side Effects & Adverse Reactions
Hypersensitivity, dizziness, syncope, vasovagal response, gastrointestinal disorders, diarrhea, abdominal pain and abdominal cramps, nausea, vomiting.
Warnings & Precautions
Prolonged excessive use may lead to fluid and electrolyte imbalance and hypokalemia. Harmful for those suffering from alcoholism. To be taken into account in pregnant or breast-feeding women, children and high-risk groups such as patients with liver disease or epilepsy.
Pharmacology & Mechanism of Action
Sodium Picosulfate is a triarylmethane group derivative stimulant laxative. After oral administration it is activated by the colonic bacteria and acts locally in the colon. The active form then stimulates the nerve endings of the intestinal wall and results in colonic peristalsis with promotion of accumulation of water and electrolytes in the colonic lumen. This results in stimulation of defecation, reduction of transit time and softening of the stool. Stimulation of the rectum causes increased motility and a feeling of rectal fullness. The rectal effect may help to restore the "call to stool".