Matropin
Generic: Homatropine Hydrobromide
Dose Regimen:
Course Duration:
Alternatives (2)Cheaper & Alternative Brands (2%)
Same active generic (Homatropine Hydrobromide), same form (Ophthalmic Solution), exact same strength (2%)
Clinical Prescribing Information
Medical monograph and safety information for healthcare professionals & patients.Indications & Clinical Uses
Hemomin eye drops is indicated for use as a mydriatic and cycloplegic.
Dosage & Administration
For refraction
: Instill two drops in the eye(s) and repeat 2-3 times at 5-10 minute intervals.
For therapy
: Instill 1-2 drops in the eye(s) every 3-4 hours.
Use in children
: Should not be used in children below the age of 3 months.
Contraindications
Contraindicated in patients with closed-angle glaucoma or with a narrow angle between the iris and the cornea.
Side Effects & Adverse Reactions
Hypersensitivity may occur as conjunctivitis.
Warnings & Precautions
Should be used with caution in patients with prostatic enlargement and in patients suffering from paralytic ileus or pyloric stenosis.
Pharmacology & Mechanism of Action
Homatropine is a competitive muscarinic receptor antagonist with a bulky aromatic group in place of the acetyl group of acetylcholine. It is expected to act in similar manner as atropine, producing similar parasympatholytic effects. By blocking muscarinic receptors and cholinergic signalling pathways, homatropine blocks the response of the iris sphincter muscle and cause the pupil to become unresponsive to light upon dilation or mydriasis. It also blocks the accommodative muscle of the ciliary body to cholinergic stimulation.