Histosin
Generic: Chlorpheniramine Maleate
Daily Dose:
Duration:
Alternatives (24)Cheaper & Alternative Brands (4 mg)
Same active generic (Chlorpheniramine Maleate), same form (Tablet), exact same strength (4 mg)
Clinical Prescribing Information
Medical monograph and safety information for healthcare professionals & patients.Indications & Clinical Uses
Alerest is indicated in the following indications-
Urticaria
Sensitivity reactions
Angioneurotic edema
Vasomotor rhinitis
Cough
Common cold
Motion sickness and
Other allergic conditions.
Dosage & Administration
Adult- Usual adult dose is 4 mg every 4-6 hours, maximum 24 mg daily.
Child-
6-12 years: 2 mg every 4-6 hours, maximum 12 mg daily.
2-5 years: 1 mg every 4-6 hours, maximum 6 mg daily.
1-2 years: 1 mg twice daily.
Below 1 year the use of Chlorpheniramine Maleate is not recommended.
Contraindications
Chlorpheniramine is contraindicated in patients hypersensitive to this agent, in newborn or premature infants.
Side Effects & Adverse Reactions
Alerest is well-tolerated, but sometimes drowsiness, dizziness, muscular weakness, and gastrointestinal upset may occur.
Warnings & Precautions
Alerest should be used with caution in patients with glaucoma and prostatic hypertrophy. During therapy with chlorpheniramine, caution should be taken in driving vehicles and operating machinery.
Pharmacology & Mechanism of Action
Chlorpheniramine Maleate is an alkylamine antihistamine. It is one of the most potent histamine H1-receptor blocking agents which is used as a potent antihistamine. This generally causes less sedation than promethazine. Chlorpheniramine Maleate exerts its effects by blocking H1-receptor competitively.