Cyclorin
Generic: Cyclosporine
Dose Regimen:
Course Duration:
Alternatives (2)Cheaper & Alternative Brands (0.05%)
Same active generic (Cyclosporine), same form (Ophthalmic Emulsion), exact same strength (0.05%)
Clinical Prescribing Information
Medical monograph and safety information for healthcare professionals & patients.Indications & Clinical Uses
Cyclorin is indicated to increase tear production in patients whose tear production is suppressed due to ocular inflammation associated with dry eye syndrome (keratoconjunctivitis sicca).
Dosage & Administration
Instill one drop of this drug twice a day in each eye approximately 12 hours apart. It can be used concomitantly with artificial tears, allowing a 15-minute interval between products.
Pediatric Use
: The safety and efficacy of cyclosporine ophthalmic Solution have not been established in pediatric patients below the age of 18.
Contraindications
Cyclosporine is contraindicated in patients with active ocular infections and in patients with known or suspected hypersensitivity to any of the ingredients in the formulation.
Side Effects & Adverse Reactions
The most common adverse event is ocular burning. Other events reported include conjunctival hyperemia, discharge, epiphora, eye pain, foreign body sensation, pruritus, stinging and visual disturbance (most often blurring).
Warnings & Precautions
Cyclorin should not be administered while wearing contact lenses. Patients with decreased tear production typically should not wear contact lenses. If contact lenses are worn, they should be removed prior to the administration of the Solution. Lenses may be reinserted 15 minutes following the administration of this medication. Cyclorin may cause blurred vision. Do not drive, use machinery, or do any activity that requires clear vision until you are sure you can perform such activities safely.
Pharmacology & Mechanism of Action
The sterile ophthalmic preparation of Cyclosporine acts as an immunomodulator in patients whose tear production is suppressed due to ocular inflammation associated with keratoconjunctivitis sicca.