Coflyt
Generic: Bromhexine Hydrochloride
Daily Dose:
Course Duration:
Alternatives (24)Cheaper & Alternative Brands (4 mg/5 ml)
Same active generic (Bromhexine Hydrochloride), same form (Syrup), exact same strength (4 mg/5 ml)
Clinical Prescribing Information
Medical monograph and safety information for healthcare professionals & patients.Indications & Clinical Uses
A-Cold is indicated in the treatment of respiratory tract disorders associated with productive cough. This include-
Tracheobronchitis
Bronchitis with emphysema
Bronchiectasis
Bronchitis with bronchospasm
Chronic inflammatory pulmonary conditions and
Pneumoconiosis.
Dosage & Administration
The recommended doses for adults and children are stated below:
Adult & Children over 12 years: 10 ml (2 teaspoons) 3 times daily
Children 6-12 years: 5 ml (1 teaspoon) 3 times daily
Children 2-6 years: 2.5 ml (1/2 teaspoon) 3 times daily
Bromhexine Hydrochloride is not recommended for children under 2 years of age without advice.
Contraindications
It is contraindicated in known hypersensitivity to Bromhexine Hydrochloride or any of the ingredients of this product.
Side Effects & Adverse Reactions
Gastrointestinal side effects may occur occasionally. A transient rise in serum aminotransferase values has been reported. Other reported side effects include-headache, vertigo (dizziness) and allergic reactions.
Warnings & Precautions
Since mucolytics may disrupt the gastric mucosa bromhexine should be used with care in patients with a history of peptic ulcer disease. Care is also advisable in asthmatic patients. Clearance of bromhexine and its metabolites may be reduced in patients with severe hepatic or renal impairment.
Pharmacology & Mechanism of Action
Bromhexine Hydrochloride is an oral mucolytic agent. It disrupts the structure of acid mucopolysaccharide fibres in mucoid sputum and produces less viscous mucus, which makes easier the expectoration. It is rapidly & completely absorbed from the gastrointestinal tract. It is widely distributed into the body tissues.