Clinail
Generic: Amorolfine Hydrochloride
Daily Dose:
Duration:
Cheaper & Alternative Brands (5% w/v)
Same active generic (Amorolfine Hydrochloride), same form (Nail Lacquer), exact same strength (5% w/v)No other brands currently registered with this exact active generic and dosage form.
Clinical Prescribing Information
Medical monograph and safety information for healthcare professionals & patients.Indications & Clinical Uses
Amofun is indicated for the treatment of
Tinea pedis (athlete's foot),
Tinea cruris,
Tinea inguinalis,
Tinea corporis,
Tinea manuum,
Pityriasis versicolor.
Dosage & Administration
To be applied to affected skin areas once daily following cleansing (in the evening). The treatment should be continued without interruption until clinical cure, and for 3 -5 days thereafter. The required duration of treatment depends on the species of fungi and on the localization of the infection. In general, treatment should be continued for at least two to three weeks. With foot mycoses, up to six weeks of therapy may be necessary or as directed by the physicians.
Use in Children and Adolescents
: Owing to the lack of clinical experience, the use of this cream in children is not recommended.
Contraindications
Amorolfine Hydrochloride cream must not be reused by patients who have shown hypersensitivity to the active substance or to any of the excipients.
Side Effects & Adverse Reactions
Adverse drug reactions like Skin and subcutaneous tissue disorders are rare and mostly mild in nature.
Warnings & Precautions
Avoid contact of Amofun cream with eyes, ears and mucous membranes. A systemic or local allergic reaction could possibly occur after use of this cream. If this happens, the cream should be stopped immediately and medical advice should be sought. Remove the cream carefully by cleaning the skin. The cream should not be reapplied.
Pharmacology & Mechanism of Action
Amorolfine is a broad spectrum topical antimycotic. It is a morpholine antifungal drug that inhibits the fungal enzymes D14 reductase and D7-D8 isomerase. This inhibition affects fungal sterol synthesis pathways & depletes ergosterol .