Citapram
Generic: Citalopram Hydrobromide
Daily Dose:
Duration:
Cheaper & Alternative Brands (10 mg)
Same active generic (Citalopram Hydrobromide), same form (Tablet), exact same strength (10 mg)No other brands are currently registered in Bangladesh for the 10 mg presentation. Below are available brands for Citalopram Hydrobromide in other strengths:
Clinical Prescribing Information
Medical monograph and safety information for healthcare professionals & patients.Indications & Clinical Uses
Arpolax is indicated for-
Depressive illness
Panic disorder
Dosage & Administration
Depressive illness:
Adult
: 20 mg daily as a single dose in the morning or evening increased if necessary to max. 60 mg daily
Elderly
: Max 40 mg daily.
Child
: Not recommended.
Panic disorder:
Adult
: Initially 10 mg daily increased to 20 mg after 7 days, usual dose 20-30 mg daily; max. 60 mg daily
Elderly
: Max 40 mg daily
Child
: Not recommended.
Contraindications
Citalopram should not be used if the patient enters a manic phase.
Side Effects & Adverse Reactions
Palpitation, postural hypotension, coughing, yawning, confusion, impaired concentration, amnesia, migraine, taste disturbance, increased salivation, rhinitis, tinnitus, micturition disorders.
Warnings & Precautions
Arpolax should be used with caution in patients with epilepsy, concurrent electroconvulsive therapy, history of mania, cardiac disease, diabetes mellitus, angle-closure glaucoma, history of bleeding disorders, hepatic and renal impairment, pregnancy and breast feeding.
Pharmacology & Mechanism of Action
Citalopram is bicyclic phthalane derivative and a selective serotonin re-uptake inhibitor, with little or no effect on noradrenaline, dopamine and GABA re-uptake. The inhibitory activity explains the antidepressant property of citalopram. It has no or very low affinity for 5-HT
1A
A, 5-HT
2A
, D
1
and D
2
receptors, α
1
, α
2
, β-adrenergic, histamine H
1
, muscarinic, cholinergic, benzodiazepine and opioid receptors.