Butakof
Generic: Butamirate Citrate
Daily Dose:
Course Duration:
Alternatives (24)Cheaper & Alternative Brands (7.5 mg/5 ml)
Same active generic (Butamirate Citrate), same form (Syrup), exact same strength (7.5 mg/5 ml)
Clinical Prescribing Information
Medical monograph and safety information for healthcare professionals & patients.Indications & Clinical Uses
Askorel is used to relieve dry (non-productive) cough. Dry cough may be caused by a recent viral infection. Askorel is also used for pre & post-operative cough, sedation in patients who will undergo surgical procedures and bronchoscopy. It can be used in the acute cough of any etiology, whooping cough and cough due to acute lower respiratory tract infections (tracheitis, laryngitis, bronchitis) etc.
Dosage & Administration
Use in adult
:
Butamirate Citrate 50 mg tablet: 2-3 tablets daily.
Butamirate Citrate syrup: 15 ml 4 times daily.
Use in children & adolescents
:
Butamirate Citrate 50 mg tablet:
Adolescent over 12 years old: 1-2 tablets daily.
Butamirate Citrate syrup:
Children (3-6 yrs): 5 ml 3 times daily.
Children (6-12 yrs): 10 ml 3 times daily.
Adolescent: 15 ml 3 times daily.
Butamirate Citrate pediatric drops:
Children ( 2 months- 1 yrs): 0.50 ml 4 times daily.
Children (1-3 yrs): 0.75 ml 4 times daily.
Contraindications
Hypersensitivity to the active ingredient.
Side Effects & Adverse Reactions
Tolerance of Askorel is good.Adverse reactions such as rash,nausea,diarrhoea and vertigo have been observed in a few rare cases,resolving after dose reduction or treatment withdrawal.
Warnings & Precautions
Askorel suppresses the cough reflex and therefore the concomitant use with expectorants should be avoided, since it may lead to mucus retention in the airways, which increases the risk of bronchospasm and respiratory infections. If the cough persists for more than 7 days (more than 3 days in children younger than12 years of age) doctor must be consulted.
Pharmacology & Mechanism of Action
Butamirate Citrate acts directly on the brain's cough center to suppress cough. Butamirate Citrate is safe and non-sedating which is neither chemically nor pharmacologically related to opium alkaloids. Butamirate Citrate is rapidly and completely absorbed after oral administration. Maximum concentration is reached within 9 hours with the sustained-release tablet. This is extremely protein-bound and plasma elimination half-life is about 13 hours. The active metabolites of Butamirate Citrate have also antitussive action.