BD MediTrimetazidine Dihydrochloride
Other Anti-anginal & Anti-ischaemic drugs
Brands & Prices (29)
📋 Indications & Uses Dosage & Administration⚠️ Contraindications⚡ Side Effects & Adverse Reactions🛡️ Warnings & Precautions🔬 Pharmacology & Mechanism
Brand Formulations & Prices
29 brands sorted by unit price
Vascare
Angimet
Trimet
Zivent MR
Angivas MR
Vastadin MR
Angimet MR
Anginox MR
Angitrim MR
Vaspec MR
Feelnor MR
Antoris MR
Trimet-MR
Anzidon MR
Cardimet MR
Metavas MR
Metazine MR
Trangina MR
Tricard MR
Vestar MR
Trangit MR
Trimacontin
Angirest
Angirid MR
Angivent MR
Metacard MR
Triginal MR
Vastarel MR
Trimacontin
📖 Official Clinical Monograph
DGDA Approved Prescribing GuidelinesAngimet is indicated in adults as add-on therapy for the symptomatic treatment of patients with stable angina pectoris who are inadequately controlled by or intolerant to first-line antianginal therapies.
Dosage & AdministrationThe recommended dose of Trimetazidine is 35 mg twice daily or 20 mg tablet thrice daily during meals. The benefit of the treatment should be assessed after three months and Trimetazidine should be discontinued if there is no treatment response.
Trimetazidine is contraindicated in patients who have hypersensitivity to the active substance or to any of the excipients. It is also is contraindicated in patients with Parkinson’s disease, parkinsonian symptoms, tremors, restless legs movement disorders, severe renal impairment.
Angimet is safe and well tolerated. The Common side effects associated with Angimet are dizziness, headache, abdominal pain, diarrhoea, dyspepsia, nausea, vomiting, rash, pruritus, urticaria and asthenia
Angimet is not a curative treatment for angina attacks, nor an initial treatment for unstable angina pectoris. It is also not a treatment for myocardial infarction.
Trimetazidine Dihydrochloride is the first 3- keto acyl CoA thiolase inhibitor (KAT), a metabolic anti-ischemic agent with proven benefits for all coronary patients. Trimetazidine Dihydrochloride inhibits fatty acid pathway by inhibiting 3-keto acyl CoA thiolase enzyme and transfers oxygen to glucose pathway. Since glucose pathway is more efficient in producing energy, the same oxygen produces more energy and makes the heart more active. Moreover, the aerobic oxidation of glucose stops production of lactic acid, which prevents angina pectoris.