BD MediPranlukast Hydrate
Leukotriene receptor antagonists
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📋 Indications & Uses Dosage & Administration⚠️ Contraindications⚡ Side Effects & Adverse Reactions🛡️ Warnings & Precautions🔬 Pharmacology & Mechanism
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📖 Official Clinical Monograph
DGDA Approved Prescribing GuidelinesPranlu oral suspension is indicated for asthma and allergic rhinitis symptoms.
Dosage & AdministrationChild
: 3.5 mg/kg bid.
Max dose
: 10 mg/kg/day (not exceeding 450 mg daily).
Adults
: Take 2 tablets (225 mg) at a time, twice a day after breakfast and dinner. The dosage may be adjusted according to your age and symptoms. Strictly follow the instructions.
Use in Children & Adolescents
: There was a substantial benefit of adding pranlukast to usual therapy in asthmatic children.
Pranlukast is contraindicated in acute asthma attacks and hepatic impairment/cirrhosis.
Headache, increased incidence of respiratory tract infection, GI disturbances, induced generalized pain, fever, myalgia and arthralgia.
Should be cautious regarding the patients with renal impairment. Possible elevations in liver enzymes can happen. Withdraw treatment in patients showing signs consistent with Churg-Strauss syndrome.
Pranlukast selectively antagonizes leukotriene D4 (LTD4) at the cysteinyl leukotriene receptor in the human airway. It inhibits the actions of LTD4 at the CysLT1 receptor and prevents airway edema, smooth muscle contraction and enhanced secretion of thick, viscous mucus.