Paracetamol + Tramadol Hydrochloride

32 Registered Brands From ৳5.00 / unit Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Brands & Prices (32) 📋 Indications & Uses Dosage & Administration⚠️ Contraindications⚡ Side Effects & Adverse Reactions🛡️ Warnings & Precautions🔬 Pharmacology & Mechanism

Brand Formulations & Prices

32 brands sorted by unit price
P-Dol

P-Dol

Popular Pharmaceuticals Ltd.
325 mg+37.5 mg · Tablet
৳ 5.00 / unit Lowest Price
Fevedol

Fevedol

Drug International Ltd.
325 mg+37.5 mg · Tablet
৳ 6.00 / unit
Tramp

Tramp

General Pharmaceuticals Ltd.
325 mg+37.5 mg · Tablet
৳ 6.02 / unit
Aceta-T

Aceta-T

Biopharma Limited
325 mg+37.5 mg · Tablet
৳ 8.00 / unit
Fapdol

Fapdol

Beacon Pharmaceuticals PLC
325 mg+37.5 mg · Tablet
৳ 8.00 / unit
NapaDol

NapaDol

Beximco Pharmaceuticals Ltd.
325 mg+37.5 mg · Tablet
৳ 8.00 / unit
Pangesic

Pangesic

Renata PLC
325 mg+37.5 mg · Tablet
৳ 8.00 / unit
Panol-T

Panol-T

Virgo Pharmaceuticals Ltd.
325 mg+37.5 mg · Tablet
৳ 8.00 / unit
Paratadol

Paratadol

Euro Pharma Ltd.
325 mg+37.5 mg · Tablet
৳ 8.00 / unit
Peratrum

Peratrum

The IBN SINA Pharmaceutical PLC
325 mg+37.5 mg · Tablet
৳ 8.00 / unit
Prodol

Prodol

Benham Pharmaceuticals Ltd.
325 mg+37.5 mg · Tablet
৳ 8.00 / unit
Resadol

Resadol

Incepta Pharmaceuticals Ltd.
325 mg+37.5 mg · Tablet
৳ 8.00 / unit
Syndol Plus

Syndol Plus

Healthcare Pharmaceuticals Ltd.
325 mg+37.5 mg · Tablet
৳ 8.00 / unit
TM Plus

TM Plus

Desh Pharmaceuticals Ltd.
325 mg+37.5 mg · Tablet
৳ 8.00 / unit
TacsDol

TacsDol

Rangs Pharmaceuticals Ltd.
325 mg+37.5 mg · Tablet
৳ 8.00 / unit
Tamenol

Tamenol

Eskayef Pharmaceuticals Ltd.
325 mg+37.5 mg · Tablet
৳ 8.00 / unit
Tempol-D

Tempol-D

Asiatic Laboratories Ltd.
325 mg+37.5 mg · Tablet
৳ 8.00 / unit
Trado Plus

Trado Plus

Pacific Pharmaceuticals Ltd.
325 mg+37.5 mg · Tablet
৳ 8.00 / unit
Tramatol

Tramatol

Somatec Pharmaceuticals Ltd.
325 mg+37.5 mg · Tablet
৳ 8.00 / unit
Atopen-X

Atopen-X

Kemiko Pharmaceuticals Ltd.
325 mg+37.5 mg · Tablet
৳ 8.02 / unit
Novodol

Novodol

Orion Pharma Ltd.
325 mg+37.5 mg · Tablet
৳ 8.02 / unit
Pyrex T

Pyrex T

Concord Pharmaceuticals Ltd.
325 mg+37.5 mg · Tablet
৳ 8.02 / unit
Xcel Max

Xcel Max

ACI Limited
325 mg+37.5 mg · Tablet
৳ 8.02 / unit
Anadol Plus

Anadol Plus

Square Pharmaceuticals PLC
325 mg+37.5 mg · Tablet
৳ 8.03 / unit
Fastdol

Fastdol

ACME Laboratories Ltd.
325 mg+37.5 mg · Tablet
৳ 8.03 / unit
Nordol

Nordol

Novelta Bestway Pharma Ltd.
325 mg+37.5 mg · Tablet
৳ 8.03 / unit
Renova T

Renova T

Opsonin Pharma Ltd.
325 mg+37.5 mg · Tablet
৳ 8.03 / unit
TRD-P

TRD-P

Mundipharma (BD) Pvt. Ltd.
325 mg+37.5 mg · Tablet
৳ 8.03 / unit
Trixotim

Trixotim

Doctor TIMS Pharmaceuticals Ltd.
325 mg+37.5 mg · Tablet
৳ 8.03 / unit
Dolceta

Dolceta

Radiant Pharmaceuticals Ltd.
325 mg+37.5 mg · Tablet
৳ 9.00 / unit
Utracet

Utracet

UniMed UniHealth Pharmaceuticals Ltd.
325 mg+37.5 mg · Tablet
৳ 9.00 / unit
Doloran Plus

Doloran Plus

SANDOZ (A Novartis Division)
325 mg+37.5 mg · Tablet
৳ 10.00 / unit

📖 Official Clinical Monograph

DGDA Approved Prescribing Guidelines
📋 Indications & Uses

This tablet is indicated for-
The management of moderate to moderately severe pain in adults.
The short-term (five days or less) management of acute pain.

Dosage & Administration

For the management of moderate to moderately severe pain
: The recommended dose is 1 or 2 tablets every 4 to 6 hours as needed for pain relief up to a maximum of 8 tablets per day.
In case of short-term (five days or less) management of acute pain
: The recommended dose is 2 tablets every 4 to 6 hours as needed for pain relief up to a maximum of 8 tablets per day.
This tablet can be administered without regard to food.

⚠️ Contraindications

Tramadol & Paracetamol combination tablets should not be administered to patients who have previously demonstrated hypersensitivity to tramadol, paracetamol, any other component of this product, or opioids. This is contraindicated in any situation where opioids are contraindicated.

⚡ Side Effects & Adverse Reactions

The following adverse reactions may happen to this therapy: asthenia, fatigue, hot flushes, dizziness, headache, tremor, abdominal pain, constipation, diarrhea, dyspepsia, dry mouth, nausea, vomiting, anorexia, anxiety, confusion, euphoria, insomnia, nervousness, somnolence pruritus, rash, increased sweating etc.

🛡️ Warnings & Precautions

Aceta-T preparation may impair mental or physical abilities required for the performance of potentially hazardous tasks such as driving a car or operating machinery.
Aceta-T preparation should not be taken with alcohol containing beverages.
The patient should be instructed not to take Aceta-T preparation in combination with other tramadol or paracetamol-containing products, including over-the-counter preparations.
Aceta-T preparation should be used with caution when taking medications such as tranquilizers, hypnotics or other opiate containing analgesics.

🔬 Pharmacology & Mechanism

Paracetamol has analgesic and antipyretic properties with weak anti-inflammatory activity. Paracetamol (Acetaminophen) is thought to act primarily in the CNS, increasing the pain threshold by inhibiting both isoforms of cyclooxygenase, COX-1, COX-2, and COX-3 enzymes involved in prostaglandin (PG) synthesis. Paracetamol is a para aminophenol derivative, has analgesic and antipyretic properties with weak anti-inflammatory activity. Paracetamol is one of the most widely used, safest and fast acting analgesic. It is well tolerated and free from various side effects of aspirin.
Tramadol is a centrally acting synthetic opioid analgesic. Although its mode of action is not completely understood, from animal tests, at least two complementary mechanisms appear applicable: binding of parent and M
1
metabolite to μ-opioid receptors and weak inhibition of the reuptake of norepinephrine and serotonin. Opioid activity is due to both low affinity binding of the parent compound and higher affinity binding of the O-demethylated metabolite M
1
to μ-opioid receptors. Tramadol has been shown to inhibit reuptake of norepinephrine and serotonin in vitro, as have some other opioid analgesics.These mechanisms may contribute independently to the overall analgesic profile of tramadol.