Ketorolac Tromethamine

236 Registered Brands From ৳4.00 / unit

Drugs used for Rheumatoid Arthritis, Non-Opioid Analgesics

Brands & Prices (236) 📋 Indications & Uses

Dosage & Administration ⚠️ Contraindications ⚡ Side Effects & Adverse Reactions 🛡️ Warnings & Precautions 🔬 Pharmacology & Mechanism

Brand Formulations & Prices

236 brands sorted by unit price

📖 Official Clinical Monograph

DGDA Approved Prescribing Guidelines

📋 Indications & Uses

Actifast is indicated for the short-term management of moderate to severe acute post-operative pain. Actifast ophthalmic solution helps relieve pain, inflammation, and light sensitivity after ocular surgery. It may also be used to decrease eye inflammation or redness caused by seasonal allergies.

Dosage & Administration

Tablet
: Recommended dose is 10 mg every 4-6 hours. It should be used short-term only (up to 7 days) and are not recommended for chronic use. Doses exceeding 40 mg/day is not recommended.
Injection
: Ketorolac injection may be used as a single or multiple doses, on a regular or when necessary schedule for the management of moderately severe, acute pain that requires analgesia at the opioid level, usually in a postoperative setting. When administering Ketorolac injection, the IV bolus must be given over no less than 15 seconds. The IM administration should be given slowly and deeply into the muscle. The analgesic effect begins within 30 minutes with maximum effect in 1 to 2 hours after dosing IV or IM. Duration of analgesic effect is usually 4 to 6 hours.
Single-Dose Treatment-
IM Dosing (Adult):
Patients <65 years of age
: One dose of 60 mg.
Patients >65 years of age, renally impaired and/or less than 50 kg of body weight
: One dose of 30 mg.
IV Dosing (Adult):
Patients <65 years of age
: One dose of 30 mg.
Patients >65 years of age, renally impaired and/or less than 50 kg of body weight
: One dose of 15 mg.
IV or IM Dosing (2 to 16 years of age):
IM Dosing
: One dose of 1 mg/kg up to a maximum of 30 mg.
IV Dosing
: One dose of 0.5 mg/kg up to a maximum of 15 mg.
Multiple-Dose Treatment (IV or IM)-
Patients <65 years of age
: The recommended dose is 30 mg Ketorolac injection every 6 hours. The maximum daily dose should not exceed 120 mg. Patients >65 years of age, renally impaired patients and patients less than 50 kg: The recommended dose is 15 mg Ketorolac injection every 6 hours. The maximum daily dose for these populations should not exceed 60 mg. For breakthrough pain, do not increase the dose or the frequency of Ketorolac Tromethamine.
Conversion from Parenteral to Oral Therapy
: Ketorolac tablets may be used either as monotherapy or as follow-on therapy to parenteral Ketorolac. When Ketorolac tablets are used as a follow-on therapy to parenteral Ketorolac, the total combined daily dose of ketorolac (oral + parenteral) should not exceed 120 mg in younger adult patients or 60 mg in elderly patients on the day the change of formulation is made. On subsequent days, oral dosing should not exceed the recommended daily maximum of 40 mg. Ketorolac IM should be replaced by Ketorolac tablet as soon as feasible. The total duration of combined parenteral and oral treatment should not exceed 5 days.
Eye Drops
: Adults: 1 drop in each eye 4 times daily.

⚠️ Contraindications

Ketorolac is contraindicated in patients having hypersensitivity to this drug or other NSAIDs. It should not be used in children under 16 years of age. lt is also contraindicated as prophylactic analgesic before surgery.

⚡ Side Effects & Adverse Reactions

Commonly occurring side effects are nausea, vomiting, gastro-intestinal bleeding, melana, peptic ulcer, pancreatitis, anxiety, drowsiness, headache, excessive thirst, fatigue, bradycardia, hypertension, palpitation, chest pain, infertility in female and pulmonary edema.

🛡️ Warnings & Precautions

Caution should be exercised in patients over the age of 65 years. Caution should also be taken in patients with active or suspected peptic ulcer or gastrointestinal bleeding or asthma and liver dysfunction.
Eye Drops: Patients with evidence of corneal epithelial breakdown should immediately discontinue use of topical NSAIDs and should be closely monitored for corneal health. Lopadol ophthalmic solution should not be administered while wearing contact lenses.

🔬 Pharmacology & Mechanism

Ketorolac Tromethamine is a potent analgesic of the non-steroidal anti-inflammatory drugs (NSAIDs). It acts by inhibiting the cyclooxygenase enzyme system and hence inhibits the prostaglandin synthesis. It demonstrates a minimal anti-inflammatory effect at its analgesic dose.

Ketorolac Tromethamine

Brand Formulations & Prices

Surgin

Ket

Apilac

Detolac

KTL

Painrel

Tromark

Rolamax

Xiroket

Kitocos

Actifast

Altorec

Analac

Apoket

Ditrolac

Doltro

Eket

Etorac

Hi-Lac

Inket

KPR

KTM

Kepros

Kerol

Ketoact

Ketolac

Ketora

Ketorolac

Ketorolac

Ketoropack

Ketoroz

Ketosav

Ketoshot

Ketovir

Kilpan

Kitorex

Knil

Korola

Lactro

Lixidol

Lupelac

Nouranz

Ostelac

Painfree

Painlok

Petorolac

Petrolac

Roket

Rolafen

Rotek

SB-Ketor

Surpim

Toro

Torolac

Tram-K

Troy

Xenolac

Xidolac

Zepac

Ketoflex

Ketoprix

Ofpain

Repopain

Sanoket

Tolec

Arolak

Ketorin

Toralin

Veslac

Emodol

Eurolac

Kerolac

Ketonaaf

Ketostar

Kflam

Temoket

Angesic

Doloket