BD MediFluphenazine + Nortriptyline
Combined anxiolytics & anti-depressant drugs
Brands & Prices (11)
📋 Indications & Uses Dosage & Administration⚠️ Contraindications⚡ Side Effects & Adverse Reactions🛡️ Warnings & Precautions🔬 Pharmacology & Mechanism
Brand Formulations & Prices
11 brands sorted by unit price
Flutrip
Anflu
Mudibak
Amival
Euphor
Fresh
Monitol
Permival
Apresin
Norzin
Norflu
📖 Official Clinical Monograph
DGDA Approved Prescribing GuidelinesAmival is indicated in-
Mild to moderate mixed anxiety/depression
Emotional disturbance
Sleep disorder
Gastric problems
Dosage & AdministrationAdults: One tablet 2 to 3 times daily.
It is contraindicated in :
History of gradual epilepsy or organic brain damage
Blood dyscrasia
Severe cardiac insufficiency
Renal or liver damage
Patients taking monoamine oxidase inhibitor (MAOI)
Younger children
Hypersensitivity to any component of the preparation
Tardive dyskinesias have been reported in phenothiazine therapy; usually after prolonged courses given at doses adequately to control psychotic illness. Blood dyscrasia, Malignant Neuroleptic syndrome and sudden death have been reported rarely. Agranulocytosis is a rare but potentially fatal adverse effect of Nortriptyline Hydrochloride.
Precautions should be taken in patients with glaucoma, prostate enlargement, cardiac failure and myocardial infarction, and in concurrent administration with CNS depressants. The drug may impair alertness and abilities to drive a car or operate machinery.
Nortriptyline hydrochloride
is a tricyclic antidepressant. Nortriptyline inhibits the uptake of norepinephrine and serotonin at nerve terminals. In contrast to its parent compound amitriptyline which is equally potent in inhibiting the uptake of norepinephrine and serotonin, Nortriptyline has a greater effect on norepinephrine reuptake than on serotonin reuptake.
Fluphenazine
is a tranquilizer of the phenothiazine type with piperazine side chain. Fluphenazine primarily acts as a neuroleptic drug whose main therapeutic effect is believed to reside in potent dopamine (specially D2) receptor antagonism.