BD MediEncephalitis Vaccine
Vaccines, Anti-sera & Immunoglobulin
Brands & Prices (1)
📋 Indications & Uses⚠️ Contraindications⚡ Side Effects & Adverse Reactions🔬 Pharmacology & Mechanism
Brand Formulations & Prices
1 brands sorted by unit price
📖 Official Clinical Monograph
DGDA Approved Prescribing GuidelinesImojev is indicated for active immunisation against Japanese encephalitis in adults, adolescents, children and infants aged 2 months and older. Imojev should be considered for use in individuals at risk of exposure through travel or in the course of their occupation.
Hypersensitivity to the active substance or to any of the excipients or to the residues protamine sulphate, formaldehyde, bovine serum albumin, host cell DNA, sodium metabisulphite, host cell protein. Individuals who show hypersensitivity reactions after receiving the first dose of the vaccine should not be given the second dose. Administration must be postponed in persons with acute severe febrile conditions.
Very common
: headache, muscle pain, injection site pain, injection site tenderness, tiredness.
Common
: Nausea, influenza like illness, fever, other injection site reactions (e.g. redness, hardening, swelling, itching).
Uncommon
: vomiting, skin rash, changes in the lymph-nodes, migraine (throbbing headache, often accompanied by nausea and vomiting and sensitivity to light), dizziness, vertigo (spinning sensation), diarrhoea, belly pain, excessive sweating, itching, chills, general condition of feeling unwell, musculoskeletal stiffness, joint pain, weakness, abnormal laboratory liver test results (hepatic enzymes increased).
The mechanism of action of Japanese encephalitis (JE) vaccines is not well understood. Studies in animals have shown that the vaccine triggers the immune system to produce antibodies against Japanese encephalitis virus that are most often protective. Challenge studies were performed in mice that were treated with human Encephalitis Vaccine antisera. These studies showed that almost all mice that had a Plaque Reduction Neutralization Test titre of at least 1:10 were protected from a lethal Japanese encephalitis virus challenge.