Clindamycin + Tretinoin

13 Registered Brands From ৳120.00 / unit Topical antibiotic & retinoid preparations
Brands & Prices (13) 📋 Indications & Uses Dosage & Administration⚠️ Contraindications⚡ Side Effects & Adverse Reactions🛡️ Warnings & Precautions🔬 Pharmacology & Mechanism

Brand Formulations & Prices

13 brands sorted by unit price

📖 Official Clinical Monograph

DGDA Approved Prescribing Guidelines
📋 Indications & Uses

Clindamycin and Tretinoin gel is indicated for the topical treatment of Acne vulgaris.

Dosage & Administration

Before sleep
: Wash the face gently with a mild soap and water, then pat the skin dry. Apply the Gel with finger tips through the face gently.
In the morning
: Apply a sunscreen after the application of Gel. Do not wash your face more than 2 or 3 times a day. Apply the sunscreen cream as needed.
Safety and effectiveness in children below 12 years of age have not been established.

⚠️ Contraindications

Clindamycin and Tretinoin should not be administered to individuals who are hypersensitive to Clindamycin or Tretinoin or any other component of the Gel.

⚡ Side Effects & Adverse Reactions

Erythema, scaling, nasopharyngitis, dry skin, cough, sinusitis and diarrhea are the common side effects.

🛡️ Warnings & Precautions

Clindamycin and Tretinoin should not be applied to eyes, nose, ear, lips, cut, burn and other infections. After the application of the Gel, keep away from sunlight.

🔬 Pharmacology & Mechanism

This is a combination of lincosamide antibiotic Clindamycin phosphate and retinoid Tretinoin. Clindamycin binds with the 50s ribosomal subunit of susceptible bacteria and prevents elongation of peptide chain by interfering with the peptidyl transfer, thereby suppressing bacterial protein synthesis. Clindamycin inhibits the activity of Propionibacterium acne as reduces the occurrence of acne. Tretinoin decreases the cohesiveness of follicular epithelial cells and increases the turn over thereby brings the comedones out.