Ceftriaxone Sodium

304 Registered Brands From ৳50.00 / unit

Third generation cephalosporins

Brands & Prices (304) 📋 Indications & Uses ⚠️ Contraindications ⚡ Side Effects & Adverse Reactions 🛡️ Warnings & Precautions 🔬 Pharmacology & Mechanism

Brand Formulations & Prices

304 brands sorted by unit price

📖 Official Clinical Monograph

DGDA Approved Prescribing Guidelines

📋 Indications & Uses

Aciphin injection is indicated for the treatment of the following major infections:
Lower respiratory tract infections
Acute Bacterial Otitis Media
Skin and skin structure infections
Urinary tract infections
Gonorrhea
Bacterial Septicemia
Bone and joint infections
Meningitis
Prevention of postoperative infections
Perioperative prophylaxis of infections associated with surgery

⚠️ Contraindications

Ceftriaxone should not be given to patients with a history of hypersensitivity to cephalosporin antibiotics.

⚡ Side Effects & Adverse Reactions

Aciphin is generally well tolerated. A few side effects such as gastro-intestinal effects including diarrhea, nausea and vomiting, stomatitis and glossitis; cutaneous reactions including rash, pruritus, urticaria, edema and erythema multiforme; hematologic reactions including eosinophilia, thrombocytopenia, leucopenia, anemia and neutropenia; hepatic reactions including elevations of SGOT or SGPT, bilirubinemia; CNS reactions including nervousness, confusion, sleep disturbances, headache, hyperactivity, convulsion, hypertonia and dizziness were reported. Local phlebitis occurs rarely following intravenous administration but can be minimized by slow injections over 2-4 minutes.

🛡️ Warnings & Precautions

As with other cephalosporins, anaphylactic shock cannot be ruled out even if a thorough patient history is taken. Anaphylactic shock requires immediate countermeasures such as intravenous epinephrine followed by a glucocorticoid. In rare cases, shadows suggesting sludge have been detected by sonograms of the gallbladder. This condition was reversible on discontinuation or completion of Aciphin therapy. Even if such findings are associated with pain, conservative, nonsurgical management is recommended. During prolonged treatment the blood picture should be checked at regular intervals.

🔬 Pharmacology & Mechanism

Ceftriaxone is a 3rd generation broad-spectrum parenteral cephalosporin antibiotic. It has potent bactericidal activity against a wide range of Gram-positive and Gram-negative organisms. Like other cephalosporins and penicillins, Ceftriaxone kills bacteria by interfering with the synthesis of the bacterial cell wall. Ceftriaxone has a high degree of stability in the presence of beta lactamases. A remarkable feature of Ceftriaxone is its relatively long plasma elimination half-life of about 6 to 9 hours, which makes single or once-daily dosage of the drug appropriate for most patients. Ceftriaxone is not metabolized in the body. About 40-65% of a dose of Ceftriaxone is excreted unchanged in the urine; the remainder is excreted in the bile and ultimately found in the feces as unchanged drug and microbiologically inactive compound. The drug is highly protein bound (95%).

Ceftriaxone Sodium

Brand Formulations & Prices

G-Ceftriax

G-Ceftriax

Parcef

G-Ceftriax

G-Ceftriax

Inoxon

Inoxon

Parcef

Triphin

Triphin

Axosin

Holicef

Nilicon

Nilicon

Perix

Perix

Topcef

Trax

Trax

Tribac

Tribac

Trimax

Ceftrix

Cefone

Rit

Arixon

Arixon

Asixone

Asixone

Axon

Axon

Eracef

Keptrix

Oryx

Oryx

Powercef

Traxon

Xone-3

Xone-3

Aciphin

Aciphin

Dicephin

Dicephin

Trizon

Vertex

Vertex

Ceftizone

Ceftizone

Enocef

Enocef

Parcef

Traxon

Nixon

Nixon

Exephin

Exephin

Cefoxguard

G-Ceftriax

G-Ceftriax

Infecef

Inoxon

Inoxon

Nilicon

Nilicon

Odatrix

Perix

Perix

Trax

Trax

Tribac

Triject

Trimax

Trimax

Rit

Parcef

Cefone

Triphin

Triphin